This donor is a healthy carrier for a genetic disease.
Please see his Genetic Testing Summary and Acknowledgment of Genetic Risk for details

Physical

Height:
5'10"
(177 cm)
Weight:
165 lb
(74 kg)
Eye Color:
Brown
Hair:
Brown/
Straight
Skin Tone:
Medium
Ancestry:
Caucasian
Blood Type:
O+
Ethnic Background:
Irish-Italian/German
Education:
MPH/Public Health
Occupation:
Data Analyst
Interests:
Camping, Cooking, Piano

Medical

Question Response
Have you or any of your family members been diagnosed with alcoholism or drug addiction?
If yes, relation and age affected:		No
Any dietary restrictions?
If yes, explain:		No
Do you wear glasses or contact lenses?
Are you near or far-sighted?		No
Allergies (medicines, food, pollens)?
If yes, please list substance and reaction caused:		Yes - Pollen: Congestion
CMV IgG AntibodyNegative
CMV IgM AntibodyNegative
Note any comments regarding above items:N/A

Family Medical History
See list of questions asked here

Your Mother
Question Response
Current age or age at death 67
Living / DeadLiving
Cause of death and any treatment prior to deathN/A
Health Problems
Healthy
Your Father
Question Response
Current age or age at death 72
Living / DeadLiving
Cause of death and any treatment prior to deathN/A
Health Problems
Healthy
Your Mother's Father
Question Response
Current age or age at death 77
Living / DeadDead
Cause of death and any treatment prior to deathInfection from hip replacement repair
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Hip injury
50
Hip replacement
Your Mother's Mother
Question Response
Current age or age at death 75
Living / DeadDead
Cause of death and any treatment prior to deathEmphysema
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Emphysema (heavy smoker)
70
Standard medical admittance, Hospice
Your Mother's Sisters 1
Question Response
Current age or age at death 70
Living / DeadDead
Cause of death and any treatment prior to deathOvarian cancer
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Ovarian cancer
30
Radiation, Chemotherapy, Implant, Surgery
Your Mother's Brothers 1
Question Response
Current age or age at death 69
Living / DeadDead
Cause of death and any treatment prior to deathKidney failure
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Kidney failure due to injury
60
Treated with dialysis, Died of complications
Your Mother's Brothers 2
Question Response
Current age or age at death 67
Living / DeadLiving
Cause of death and any treatment prior to deathN/A
Health Problems
Healthy
Your Father's Father
Question Response
Current age or age at death 56
Living / DeadDead
Cause of death and any treatment prior to deathHeart attack
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Heart attack
56
Fatal
Your Father's Mother
Question Response
Current age or age at death 81
Living / DeadDead
Cause of death and any treatment prior to deathPneumonia
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Pneumonia
81
Fatal
Your Father's Sisters 1
Question Response
Current age or age at death 76
Living / DeadLiving
Cause of death and any treatment prior to deathN/A
Health Problems
Healthy
Your Father's Brothers 1
Question Response
Current age or age at death 74
Living / DeadLiving
Cause of death and any treatment prior to deathN/A
Health Problems
Healthy

Religion:

Faith None
Denomination Atheist

Updates to Profile

Update AvailableYes
Updates - PersonalNo change to profile: October 2020, January 2021, January 2022. Update received September 2025: Donor reports that he is now married. No change to profile: May 2026.
Updates - MedicalNo change to profile: Ocotber 2020, January 2021, January 2022. Update October 2024: The donor has been found to be a healthy carrier for Cystic Fibrosis (gene CFTR). His prior testing in 2020 did not report him to be positive for CFTR, as the variant was not classified as disease causing by the lab Sema4 at that time. All recipients should be tested for CFTR and be negative before using this donor. See details on his genetic testing download. No change to profile: September 2025, May 2026.
Updates - Family Medical HistoryNo change to profile: October 2020, January 2021. Update received January 2022: Maternal Uncle #2 had a minor stroke at age 66, associated hypertension treated with statins. Update received June 2023: Donor was asked for more information about his maternal aunt’s ovarian cancer diagnosis at age 30. This was diagnosed some 40 years ago when no genetic testing was available. The donor asked his mother and the aunt’s husband if genetic testing was performed later, and the response was no. Update received September 2025: Maternal Uncle #2 has died from kidney failure, age of death unreported. UPDATE April 2026: Fairfax was notified that a child conceived with this donor may have a genetic condition that affects their teeth. This case is currently under Investigation. Additional information will be added once obtained. UPDATE May 2026: Fairfax was notified that two other clients have children conceived with this donor who may also have a genetic condition that affects their teeth. No genetic testing has been conducted on those affected at this point. Should a genetic variant be identified in an affected child, results will be requested for review and determination of next steps. The donor reports that, after talking with his mother, he was told that his baby teeth had “weak enamel”. Though he requested additional information, no records of this history were available. He reports that the enamel on his adult teeth “isn't perfect. I use whitening toothpaste, but I don't have any particular sensitivity to cold/heat and I've never had a cavity. I had my wisdom teeth removed and had braces due to some crowding, but no issues with tooth loss, chronic gum issues, etc.” He also reported the following, “Thinking about this, I know my dad's teeth do have a bit of roughness/discoloration (i.e., imperfect enamel) as well as some crowding - not to a particularly great extent.” He denied any personal or family history of bone issues, cornea discoloration, and hearing loss. No change to profile: May 2026. UPDATE June 2026: A client reported 3 EIFs during her 20 weeks ultrasound. She requested the Vistara panel which came back positive for Rett syndrome (RS). A subsequent amniocentesis confirmed a diagnosis of RS due to a pathogenic variant in the MECP2 gene. These results, along with the client’s negative MECP2 testing were shared with Fairfax for review. Pathogenic variants in the MECP2 gene cause X-linked RS. RS is a progressive neurodevelopmental condition with multiple forms. Being X-linked, RS mostly affects females with a single MEPC2 variant; rarely males with a single MEPC2 variant have been described with symptoms ranging from severe neonatal encephalopathy to mild intellectual disabilities. The majority of MEPC2 variants are de novo, although inheritance from an unaffected parent with gonadal mosaicism has been reported. By definition, genetic testing cannot rule out gonadal mosaicism. Recent literature has suggested that up to 28% of males have variants in the MEPC2 gene in their sperm. As such, even if the donor was tested and found to have a percent of sperm with an MEPC2 variant, the risk for him to have a child with Rett syndrome would not be higher than the risk in the general population of reproducing males. As such, Fairfax has elected not to test the donor’s sperm for the MEPC2 variant identified in this child. UPDATE June 2026: A client’s child was identified to have a likely pathogenic variant (c.920dup) in the FAM83H gene. The egg source has not yet been tested, however, given the number of donor conceived children reported to have dental issues, Fairfax has elected to reach out to the donor to obtain consent in order to test him for this variant. No timeline for this process is currently available. UPDATE June 2026: The donor granted consent to targeted testing for the FAM83H variant discussed above. Testing has been ordered. Updates will be provided when available. UPDATE July 2026: Donor 6163 has been identified to carry a likely pathogenic variant (c.920dup) in his FAM83H gene. The donor was tested for this variant after a donor conceived child was identified to have this variant, which was not identified in the child’s mother. This genetic change has been associated with amelogenesis imperfecta Type III, which causes soft tooth enamel that breaks down easily. Any child conceived with this donor’s sperm has a 50% chance to inherit this variant and have this condition. Those with embryos, a pregnancy, or children from this donor are encouraged to share this information with your fertility specialist and your child’s pediatrician and dentist to discuss their personal medical management recommendations. As the donor has been identified to have a variant in this gene, testing your embryos, pregnancy, or children for this variant may be an option. You may consider meeting with a clinical genetic counselor. A genetic counselor can help you understand this information in more detail and talk about these testing options. UPDATE July 2026: A client reported that she has two children conceived by this donor and that the older of the two was diagnosed at the age of two with autism, intellectual disability, moderate global development delay, speech delay, and a large head. Her other child is reportedly healthy. The affected child will be pursuing whole genome sequencing. No timeline for results is currently available. To be clear, there is no indication that this child's medical history is linked solely, if at all, to the donor. Additional information will be added when available.