Physical
Medical
Family Medical History
Religion
Updates to ProfileThis donor is a healthy carrier for a genetic disease.
Please see his Genetic Testing Summary and Acknowledgment of Genetic Risk for details
Please see his Genetic Testing Summary and Acknowledgment of Genetic Risk for details
Physical
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Height:
5'11"
(180 cm) |
Weight:
180 lb
(81 kg) |
Eye Color:
Brown
|
Hair:
Brown/
Wavy |
Skin Tone:
Medium Light
|
Ancestry:
Caucasian
|
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Blood Type:
B+
|
Ethnic Background:
English-Scottish/Italian-Hungarian
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Education:
Pursuing PhD/Engineering
|
Occupation:
Student
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Interests:
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Cooking with family, Hiking, Reading, Volleyball
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Medical
| Question | Response |
| Have you or any of your family members been diagnosed with alcoholism or drug addiction? If yes, relation and age affected: | No |
| Any dietary restrictions? If yes, explain: | No |
| Do you wear glasses or contact lenses? Are you near or far-sighted? | No |
| Allergies (medicines, food, pollens)? If yes, please list substance and reaction caused: | No |
| CMV IgG Antibody | Negative |
| CMV IgM Antibody | Negative |
| Note any comments regarding above items: | N/A |
Family Medical HistorySee list of questions asked here
Your Mother
| Question | Response |
| Current age or age at death | 53 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Other
Gall bladder removed at age 38 after complicated birth
Your Father
| Question | Response |
| Current age or age at death | 59 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Migraines
38
OTC medication
Brothers
Your Brother 1
| Question | Response |
| Current age or age at death | 21 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Healthy
Sisters
Your Sister 1
| Question | Response |
| Current age or age at death | 27 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Healthy
Your Sister 2
| Question | Response |
| Current age or age at death | 15 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Healthy
Your Mother's Father
| Question | Response |
| Current age or age at death | 70 |
| Living / Dead | Dead |
| Cause of death and any treatment prior to death | Unknown-general health decline, estranged from family |
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Other
Health problems unknown due to estrangement.
Your Mother's Mother
| Question | Response |
| Current age or age at death | 77 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Other
Paralyzed in an accident age 35
Your Mother's Sisters 1
| Question | Response |
| Current age or age at death | 50 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Healthy
Your Mother's Brothers 1
| Question | Response |
| Current age or age at death | 54 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Healthy
Your Father's Father
| Question | Response |
| Current age or age at death | 75 |
| Living / Dead | Dead |
| Cause of death and any treatment prior to death | Poor general health, heavy smoker |
Health Problems
Disease
Age Diagnosed
Treatment For Condition
High blood pressure
60
Medication
High cholesterol
60
Lifestyle changes
Pancreatic Cancer
65
Chemotherapy
Your Father's Mother
| Question | Response |
| Current age or age at death | 86 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Disease
Age Diagnosed
Treatment For Condition
Other
Knee replacement, age 76
Your Father's Brothers 1
| Question | Response |
| Current age or age at death | 55 |
| Living / Dead | Living |
| Cause of death and any treatment prior to death | N/A |
Health Problems
Healthy
Religion:
| Faith | None |
| Denomination | NA |
Updates to Profile
| Update Available | N/A |
| Updates - Personal | N/A |
| Updates - Medical | UPDATE Dec 2025: Donor 6188 has been identified to carry a variant of uncertain significance (c.569T>G (p.Leu190Arg)) in the EPHB4 gene. Genetic variants in the EPHB4 gene have been associated with capillary malformation–arteriovenous malformation type 2 (CM-AVM2) and EPHB4-related lymphatic conditions. |
| Updates - Family Medical History | UPDATE Oct 2025: Fairfax was notified that a client’s son was diagnosed with an arteriovenous malformation (AVM) at 15 months of age by a dermatologist, following the identification of multiple capillary malformations across his body. Additional signs, symptoms, and medical concerns have included poor sucking, gagging, torticollis (which required physical therapy), positional plagiocephaly (managed with a helmet), a heart murmur (no echocardiogram performed), and failure tothrive. Per the client, genetic testing on the child identified a variant of uncertain significance in the EPHB4 gene. Fairfax has requested these results from the client. When a variant of uncertain significance (VUS) is identified, it is unclear whether that variant is associated with a specific health condition. In many cases, the variant is so rare in the general population that it has not been described in the literature or variant databases, thus there is little published information to review. Identification of a variant of uncertain significance does not establish or rule out the diagnosis of a disorder and no medical management recommendations are made based solely on the finding of a VUS. As such, no underlying cause is known atat this point, nor has any link to this donor been identified. Seven other births have been reported to Fairfax with no medical concerns.UPDATE Nov 2025: Fairfax has been informed that a second client reports that her child has similiar markings as the first client's child above. No medical evaluations have been conducted on this child to date.UPDATE Nov 2025: Fairfax was notified that a client's son was identified to have red spots on his skin that may be related to a vascular malformation. This is the third report of similiar findings for children conceived by this donor. Per the client, genetic testing was conducted on her child though the client was unable to provide information regarding the specific results of that testing. Fairfax has requested these results from the client.UPDATE Dec 2025: Clients 1 and 3 above have independently reported that their child have the same genetic variant in the same gene (EPHB4 (c.569T>G (p.Leu190Arg))). Both labs have clasified this finding as a VUS. Testing has been ordered on this donor. UPDATE Dec 2025: A fourth client has reached out to inform Fairfax that her daughter has similiar markings as the children of the above clients. No medical evaluations have been conducted on this child to date.UPDATE Dec 2025: Fairfax reached out to the donor to determine if he or any of his relatives have symptoms related to EPHB4-Capillary malformation-arteriovenous malformation (EPHB4-CM-AVM), including Capillary malformations (CMs), Arteriovenous malformations (AVMs) or arteriovenous fistulas (AVFs), and Nosebleeds. The donor denies being aware of any personal or family history. UPDATE 2025: Donor 6188 has been identified to carry a variant of uncertain significance (c.569T>G (p.Leu190Arg)) in the EPHB4 gene. Genetic variants in the EPHB4 gene have been associated with capillary malformation–arteriovenous malformation type 2(CM-AVM2) and EPHB4-related lymphatic conditions. There is a 50% chance for any embryo, pregnancy, or child conceived with this donor to inherit this variant of uncertain significance. At present, eight births with the use of this donor have been reported to Fairfax Cryobank. Four donor-conceived children have reported skin findings that are consistent with CM-AVM2. No children have reported more serious symptoms nor have any reported findings consistent with EPHB4-related lymphatic conditions. Though the VUS identified in the donor and two donor-conceived children has not been documented to cause health conditions in major medical or population databases and the literature does not support that this is a disease-causing variantbased on the findings in multiple donor-conceived children with features of CM-AVM2, we strongly believe that this variant is disease-causing. |