{"id":4094,"date":"2015-10-23T13:14:57","date_gmt":"2015-10-23T13:14:57","guid":{"rendered":"https:\/\/fairfaxcryobank.com\/hpv-faqs\/"},"modified":"2020-03-10T19:40:29","modified_gmt":"2020-03-10T19:40:29","slug":"hpv-faqs","status":"publish","type":"page","link":"https:\/\/fairfaxcryobank.com\/uk\/hpv-faqs","title":{"rendered":"HPV FAQs"},"content":{"rendered":"\t<ul class=\"faqs\" >\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">What does FDA require for HPV detection?<\/div>\n\t\t\t<div class=\"-answer\"><p>The FDA requires screening donors for HPV by physical exam and medical histories but does not require HPV DNA based testing of sperm donors.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">What is Fairfax Cryobank doing for HPV detection?<\/div>\n\t\t\t<div class=\"-answer\"><p>Fairfax Cryobank screens donors for HPV by medical history and physical exam, meeting the FDA standard. In addition we exceed the standard, having added DNA based testing of donor sperm in 2001. We are looking for the two strains of HPV that are most frequently associated with cervical cancer.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">What is the medical evidence that supports this additional testing?<\/div>\n\t\t\t<div class=\"-answer\"><p>We cite a study (Human Papillomavirus DNA Detection in Sperm Using Polymerase Chain Reaction, Obstet Gynecol 2001;97:357-60) that concludes: &#8220;HPV is present in sperm cells from infected and apparently healthy subjects, and sperm washing does not eliminate the risk of HPV transmission to recipients. We suggest that HPV DNA testing should be done on the semen of prospective donors, and those with positive tests should be excluded from donation.&#8221;<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">Why is Fairfax doing more than is required by the FDA?<\/div>\n\t\t\t<div class=\"-answer\"><p>Our view is that self-reported medical histories and physical examinations are insufficient to screen for HPV and that a DNA based test provides an additional level of safety to our donor sperm. At Fairfax Cryobank we believe that all donor sperm should be both screened for HPV and tested for the most prevalent strains of HPV that cause cervical cancer. The medical literature supports our position.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">How is the testing for HPV performed on the donors?<\/div>\n\t\t\t<div class=\"-answer\"><p>We test the semen of our donors for HPV at the time they are being screened for initial donor eligibility, and thereafter every three months while they are donating. By testing semen samples at 3 month intervals, we increase the chances of detecting the presence of HPV earlier than via the visual detection methods typically performed during a routine physical examination given at 6 month intervals in most tissue banking operations.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">Is the lab doing the HPV DNA test experienced with this kind of testing?<\/div>\n\t\t\t<div class=\"-answer\"><p>The protocol and validation of our HPV testing was developed at the Molecular Infectious Disease Laboratory (MIDL) of the Genetics &amp; IVF Institute. MIDL was established in 1998, and is a cutting edge CLIA certified facility dedicated to infectious disease diagnostics using exclusively high sensitivity PCR (DNA) amplification methods. All in-house protocols presently in use must pass a multi-part validation process. Prior to offering the HPV test in 2001 approximately 10,000 assays were performed.<br \/>\nIn addition to supporting the activities of various GIVF divisions, of which Fairfax Cryobank is one, MIDL provides high priority testing for prenatal and neonatal units for hospitals in the Washington, D.C. metro. MIDL is directed by Brian D. Mariani, Ph.D., who has 25 years experience in molecular genetics, microbiology and biotechnology. Trained at Stanford and Harvard universities, Dr. Mariani has applied his expertise at MIDL to the design of molecular genetic-based detection assays for a variety of infectious microorganisms from diverse clinical specimen types.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">Has the testing accuracy been validated by outside agencies?<\/div>\n\t\t\t<div class=\"-answer\"><p>The Molecular Infectious Disease Lab (MIDL) of Genetics &amp; IVF Institute performs in-house validated assays under CLIA certification (#49D0952503) according to all established guidelines. The lab director is qualified for Molecular Virology under N.Y. State Dept of Health guidelines. The lab participates in the College of American Pathology nucleic-acid amplification survey program (including HPV detection) and maintains a 100% accuracy score.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t\t<li class=\"faq\" id=\"faq-block_5d13d515524bb\">\n\t\t\t<div class=\"-question\">Why aren&#8217;t all sperm banks offering this testing?<\/div>\n\t\t\t<div class=\"-answer\"><p>It is expensive and requires a relationship with a sophisticated infectious disease laboratory that has experience with semen testing. Fairfax Cryobank has benefited tremendously from our relationship with <a href=\"https:\/\/www.givf.com\/\">Genetics &amp; IVF Institute<\/a>, our parent company. Since our inception as a sperm bank, we have always been at the forefront of genetic screening of our donors.<\/p>\n<\/div>\n\t\t<\/li>\n\t\t<\/ul>\n<script>\nvar faqs = document.querySelectorAll('li.faq');\nfor (var i=0; i<faqs.length; i++) {\n\tfaqs[i].addEventListener('click', function(event) {\n\t\tthis.classList.toggle('-expanded');\n\t});\n}\n<\/script>\n<style>\nul.faqs {\n\tmargin: 0 0 25px; padding: 0;\n}\nul.faqs > li.faq {\n\tmargin: 0 0 10px; padding: 0;\n\tlist-style: none;\n\tbackground: none;\n}\nul.faqs > li.faq.-expanded {\n\tborder: 1px solid #e8e8e8;\n\tbox-shadow: 0 2px 10px rgba(0,0,0,0.1)\n}\nul.faqs > li.faq .-question {\n\tposition: relative;\n\tpadding: 19px 19px 19px 78px;\n\tcolor: #565456;\n\tfont-size: 20px; line-height: 1.2;\n\tbackground: #f1f1f1;\n\tcursor: pointer;\n\ttransition: .3s\n}\nul.faqs > li.faq .-question:hover { color: #1f1f1f; background: #f6f6f6; }\nul.faqs > li.faq .-question:before {\n\tcontent: \"\";\n\tposition: absolute;\n\ttop: 0; bottom: 0; left: 0;\n\twidth:62px;\n\tbackground: linear-gradient(#898989,#898989), linear-gradient(#898989,#898989), #eaeaea;\n\tbackground-position:center;\n\tbackground-size: 20px 2px,2px 20px;\n\tbackground-repeat:no-repeat;\n}\nul.faqs > li.faq .-question:hover:before {\n\tbackground: linear-gradient(#ea6950,#ea6950), linear-gradient(#ea6950,#ea6950), #eaeaea;\n\tbackground-position:center;\n\tbackground-size: 20px 2px,2px 20px;\n\tbackground-repeat:no-repeat;\n}\nul.faqs > li.faq.-expanded .-question,\nul.faqs > li.faq.-expanded .-question:hover { color: #ea6950; background: #f9f9f9; }\nul.faqs > li.faq.-expanded .-question:before,\nul.faqs > li.faq.-expanded .-question:hover:before {\n\tcontent: \"\";\n\tposition: absolute;\n\ttop: 0; bottom: 0; left: 0;\n\twidth:62px;\n\tbackground: linear-gradient(#ffffff,#ffffff), #ea6950;\n\tbackground-position:center;\n\tbackground-size: 20px 2px;\n\tbackground-repeat:no-repeat;\n}\n\nul.faqs > li.faq .-answer {\n\toverflow: hidden;\n\tpadding: 0 0 0 78px;\n\tmax-height: 0;\n\ttransition: 0.2s;\n}\nul.faqs > li.faq .-answer > * { overflow: hidden; max-height: 0; }\nul.faqs > li.faq.-expanded .-answer {\n\tbox-sizing: border-box;\n\tpadding: 19px 19px 19px 78px;\n\tmax-height: 9999px;\n\tcolor: #585858;\n\tfont-size: 16px; line-height: 23px;\n\tbackground: #fff;\n\ttransition: 0.4s;\n}\nul.faqs > li.faq.-expanded .-answer > * { max-height: 9999px;}\n<\/style>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4094","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HPV FAQs | Fairfax Cryobank<\/title>\n<meta name=\"description\" content=\"Curious about Fairfax Cryobank&#039;s HPV screening for sperm donors? 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